NGLY1 protein (Latimeria chalumnae) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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[Homology]

Score

NGLY1

N-glycanase 1. (659 aa)

Predicted Functional Partners:

VCP

0.988

PSMC1

0.979

DERL1

0.973

LOC102365663

0.971

UBXN1

0.957

RAD23B

0.940

RAD23A

0.940

LOC102353696

0.940

ENGASE

0.923

NSFL1C

0.876

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DERL1	LOC102353696	ENSLACP00000008715	ENSLACP00000020796	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.690
DERL1	LOC102365663	ENSLACP00000008715	ENSLACP00000018103	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Zgc:136908; Belongs to the AAA ATPase family.	0.981
DERL1	NGLY1	ENSLACP00000008715	ENSLACP00000002404	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	N-glycanase 1.	0.973
DERL1	NSFL1C	ENSLACP00000008715	ENSLACP00000013239	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NSFL1 cofactor.	0.824
DERL1	PSMC1	ENSLACP00000008715	ENSLACP00000016007	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.	0.934
DERL1	RAD23A	ENSLACP00000008715	ENSLACP00000016998	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	RAD23 homolog A, nucleotide excision repair protein.	0.690
DERL1	RAD23B	ENSLACP00000008715	ENSLACP00000004049	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	RAD23 homolog B, nucleotide excision repair protein.	0.690
DERL1	UBXN1	ENSLACP00000008715	ENSLACP00000020412	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain protein 1.	0.972
DERL1	VCP	ENSLACP00000008715	ENSLACP00000013937	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein.	0.995
ENGASE	NGLY1	ENSLACP00000021003	ENSLACP00000002404	Endo-beta-N-acetylglucosaminidase.	N-glycanase 1.	0.923
LOC102353696	DERL1	ENSLACP00000020796	ENSLACP00000008715	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.690
LOC102353696	LOC102365663	ENSLACP00000020796	ENSLACP00000018103	Uncharacterized protein.	Zgc:136908; Belongs to the AAA ATPase family.	0.805
LOC102353696	NGLY1	ENSLACP00000020796	ENSLACP00000002404	Uncharacterized protein.	N-glycanase 1.	0.940
LOC102353696	PSMC1	ENSLACP00000020796	ENSLACP00000016007	Uncharacterized protein.	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.	0.924
LOC102353696	UBXN1	ENSLACP00000020796	ENSLACP00000020412	Uncharacterized protein.	UBX domain protein 1.	0.743
LOC102353696	VCP	ENSLACP00000020796	ENSLACP00000013937	Uncharacterized protein.	Valosin containing protein.	0.870
LOC102365663	DERL1	ENSLACP00000018103	ENSLACP00000008715	Zgc:136908; Belongs to the AAA ATPase family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.981
LOC102365663	LOC102353696	ENSLACP00000018103	ENSLACP00000020796	Zgc:136908; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.805
LOC102365663	NGLY1	ENSLACP00000018103	ENSLACP00000002404	Zgc:136908; Belongs to the AAA ATPase family.	N-glycanase 1.	0.971
LOC102365663	NSFL1C	ENSLACP00000018103	ENSLACP00000013239	Zgc:136908; Belongs to the AAA ATPase family.	NSFL1 cofactor.	0.989