Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H2ZYD7_LATCHProtein kinase domain-containing protein. (330 aa)    
Predicted Functional Partners:
CD247
CD247 molecule.
   
 0.952
ZAP70
Tyrosine-protein kinase.
   
 0.942
LYN
Tyrosine-protein kinase.
   
 0.928
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 0.915
SYK
Tyrosine-protein kinase.
   
 0.904
DOK2
Docking protein 2.
   
 0.894
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
   
 0.872
LCP2
Lymphocyte cytosolic protein 2.
   
 0.865
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.849
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1.
    
 0.838
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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