Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2ZYE4_LATCHFli-1 proto-oncogene, ETS transcription factor b. (470 aa)    
Predicted Functional Partners:
GATA1
GATA binding protein 1b.
    
 0.714
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
    
 0.668
UPP1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
    
 
 0.659
PLXND1
Plexin D1.
   
  
 0.657
CLIC2
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.655
AR
Androgen receptor.
    
 
 0.653
MYB
MYB proto-oncogene, transcription factor.
     
 0.602
SPI1
Spi-1 proto-oncogene.
   
 0.509
SPIB
ETS domain-containing protein.
   
 0.509
SRF
Serum response factor.
    
 0.503
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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