STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDX4Peroxiredoxin 4. (269 aa)    
Predicted Functional Partners:
TXNDC5
Thioredoxin domain containing 5.
  
 0.948
ERP44
Endoplasmic reticulum protein 44.
  
 0.917
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
  
 0.907
SRXN1
Sulfiredoxin.
   
 0.877
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.867
LOC102354290
Uncharacterized protein.
  
 0.858
LOC102347712
Thioredoxin; Belongs to the thioredoxin family.
  
 0.856
TXN2
Thioredoxin 2.
  
 0.805
M3XI97_LATCH
Thioredoxin domain-containing protein.
  
 0.801
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.727
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.