STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lach-UD-01Ig-like domain-containing protein; Belongs to the MHC class I family. (342 aa)    
Predicted Functional Partners:
CALR3
Calreticulin.
   
 
  0.703
H3AVH0_LATCH
Uncharacterized protein.
    
  0.693
LOC106706091
Uncharacterized protein.
     
  0.680
PDIA3
Protein disulfide-isomerase.
     
  0.680
H3AJ79_LATCH
Ig-like domain-containing protein.
     
  0.650
RPA2
Replication protein A2.
   
 0.463
LOC102350052
MHC_I-like_Ag-recog domain-containing protein.
  
  0.435
H2ZWA0_LATCH
Uncharacterized protein.
   
 0.423
STN1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
   
 0.423
SASS6
SAS-6 centriolar assembly protein.
   
 0.423
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.