GGH protein (Latimeria chalumnae) - STRING interaction network

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Score

GGH

Folate gamma-glutamyl hydrolase. (314 aa)

Predicted Functional Partners:

FPGS

0.939

DHFR

0.919

LOC102346348

0.919

UEVLD

0.702

GART

0.560

SLC19A1

0.443

ATIC

0.428

ARL13B

0.424

RFC1

0.420

TPMT

0.418

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL13B	GGH	ENSLACP00000008225	ENSLACP00000002463	ADP ribosylation factor like GTPase 13B.	Folate gamma-glutamyl hydrolase.	0.424
ATIC	DHFR	ENSLACP00000004507	ENSLACP00000007736	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Dihydrofolate reductase.	0.955
ATIC	FPGS	ENSLACP00000004507	ENSLACP00000019432	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.726
ATIC	GART	ENSLACP00000004507	ENSLACP00000022410	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.999
ATIC	GGH	ENSLACP00000004507	ENSLACP00000002463	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Folate gamma-glutamyl hydrolase.	0.428
ATIC	LOC102346348	ENSLACP00000004507	ENSLACP00000008378	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Zgc:153031; Belongs to the dihydrofolate reductase family.	0.955
ATIC	RFC1	ENSLACP00000004507	ENSLACP00000003355	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Replication factor C subunit 1.	0.505
DHFR	ATIC	ENSLACP00000007736	ENSLACP00000004507	Dihydrofolate reductase.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.955
DHFR	FPGS	ENSLACP00000007736	ENSLACP00000019432	Dihydrofolate reductase.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.997
DHFR	GART	ENSLACP00000007736	ENSLACP00000022410	Dihydrofolate reductase.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.975
DHFR	GGH	ENSLACP00000007736	ENSLACP00000002463	Dihydrofolate reductase.	Folate gamma-glutamyl hydrolase.	0.919
DHFR	LOC102346348	ENSLACP00000007736	ENSLACP00000008378	Dihydrofolate reductase.	Zgc:153031; Belongs to the dihydrofolate reductase family.	0.910
FPGS	ATIC	ENSLACP00000019432	ENSLACP00000004507	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.726
FPGS	DHFR	ENSLACP00000019432	ENSLACP00000007736	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Dihydrofolate reductase.	0.997
FPGS	GART	ENSLACP00000019432	ENSLACP00000022410	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.735
FPGS	GGH	ENSLACP00000019432	ENSLACP00000002463	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Folate gamma-glutamyl hydrolase.	0.939
FPGS	LOC102346348	ENSLACP00000019432	ENSLACP00000008378	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Zgc:153031; Belongs to the dihydrofolate reductase family.	0.997
FPGS	RFC1	ENSLACP00000019432	ENSLACP00000003355	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Replication factor C subunit 1.	0.468
FPGS	SLC19A1	ENSLACP00000019432	ENSLACP00000009848	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Solute carrier family 19 member 1.	0.418
GART	ATIC	ENSLACP00000022410	ENSLACP00000004507	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.999