GGH protein (Latimeria chalumnae) - STRING interaction network

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Score

GGH

Folate gamma-glutamyl hydrolase. (314 aa)

Predicted Functional Partners:

FPGS

0.944

DHFR

0.923

LOC102346348

0.916

QDPR

0.675

PTPDC1

0.661

LOC102350220

0.659

H3AKV7_LATCH

0.659

SLC19A1

0.641

PEX7

0.632

TPMT

0.615

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHFR	FPGS	ENSLACP00000007736	ENSLACP00000019432	Dihydrofolate reductase.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.994
DHFR	GGH	ENSLACP00000007736	ENSLACP00000002463	Dihydrofolate reductase.	Folate gamma-glutamyl hydrolase.	0.923
DHFR	LOC102346348	ENSLACP00000007736	ENSLACP00000008378	Dihydrofolate reductase.	Zgc:153031; Belongs to the dihydrofolate reductase family.	0.909
DHFR	QDPR	ENSLACP00000007736	ENSLACP00000016584	Dihydrofolate reductase.	Quinoid dihydropteridine reductase.	0.975
DHFR	SLC19A1	ENSLACP00000007736	ENSLACP00000009848	Dihydrofolate reductase.	Solute carrier family 19 member 1.	0.511
FPGS	DHFR	ENSLACP00000019432	ENSLACP00000007736	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Dihydrofolate reductase.	0.994
FPGS	GGH	ENSLACP00000019432	ENSLACP00000002463	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Folate gamma-glutamyl hydrolase.	0.944
FPGS	LOC102346348	ENSLACP00000019432	ENSLACP00000008378	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Zgc:153031; Belongs to the dihydrofolate reductase family.	0.994
FPGS	QDPR	ENSLACP00000019432	ENSLACP00000016584	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Quinoid dihydropteridine reductase.	0.763
FPGS	SLC19A1	ENSLACP00000019432	ENSLACP00000009848	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Solute carrier family 19 member 1.	0.568
GGH	DHFR	ENSLACP00000002463	ENSLACP00000007736	Folate gamma-glutamyl hydrolase.	Dihydrofolate reductase.	0.923
GGH	FPGS	ENSLACP00000002463	ENSLACP00000019432	Folate gamma-glutamyl hydrolase.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.944
GGH	H3AKV7_LATCH	ENSLACP00000002463	ENSLACP00000010278	Folate gamma-glutamyl hydrolase.	Uncharacterized protein.	0.659
GGH	LOC102346348	ENSLACP00000002463	ENSLACP00000008378	Folate gamma-glutamyl hydrolase.	Zgc:153031; Belongs to the dihydrofolate reductase family.	0.916
GGH	LOC102350220	ENSLACP00000002463	ENSLACP00000000522	Folate gamma-glutamyl hydrolase.	Dipeptidyl-peptidase 6b; Belongs to the peptidase S9B family.	0.659
GGH	PEX7	ENSLACP00000002463	ENSLACP00000000044	Folate gamma-glutamyl hydrolase.	Peroxisomal biogenesis factor 7.	0.632
GGH	PTPDC1	ENSLACP00000002463	ENSLACP00000020075	Folate gamma-glutamyl hydrolase.	TYR_PHOSPHATASE_2 domain-containing protein.	0.661
GGH	QDPR	ENSLACP00000002463	ENSLACP00000016584	Folate gamma-glutamyl hydrolase.	Quinoid dihydropteridine reductase.	0.675
GGH	SLC19A1	ENSLACP00000002463	ENSLACP00000009848	Folate gamma-glutamyl hydrolase.	Solute carrier family 19 member 1.	0.641
GGH	TPMT	ENSLACP00000002463	ENSLACP00000006107	Folate gamma-glutamyl hydrolase.	Thiopurine S-methyltransferase.	0.615