Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (373 aa)    
Predicted Functional Partners:
HDAC4
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 0.918
HDAC5
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 0.918
DCX
Uncharacterized protein.
 
  
 
 0.903
LOC102361440
Si:ch73-60h1.1.
  
  
 
0.901
DCLK2-2
Uncharacterized protein.
 
  
   0.899
LOC102361286
Calmodulin 2; Belongs to the calmodulin family.
    
 0.894
CALML6
Calmodulin like 6.
    
 0.874
CREB1
cAMP responsive element binding protein 1.
    
 0.857
MPP1
Membrane palmitoylated protein 1; Belongs to the MAGUK family.
 
 
  0.757
CALML4
Calmodulin like 4.
    
 0.747
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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