Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DLX6Distal-less homeobox 6. (266 aa)    
Predicted Functional Partners:
DLX5
Distal-less homeobox 5.
  
 
0.875
HAND2
Heart and neural crest derivatives expressed 2.
    
 
 0.628
EDN1
Endothelin 1.
      
 0.590
EDNRA
Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.
      
 0.566
BMP4
Bone morphogenetic protein 4.
     
 0.549
H3AFZ6_LATCH
Fraser extracellular matrix complex subunit 1.
   
  
 0.546
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.533
HOPX
Homeobox domain-containing protein.
     
 0.507
FGF22
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.502
RUNX2
Runt-related transcription factor.
   
 0.496
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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