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STRINGSTRING
ASXL1 protein (Latimeria chalumnae) - STRING interaction network
"ASXL1" - Additional sex combs like 1 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASXL1Additional sex combs like 1 (Drosophila) (1490 aa)    
Predicted Functional Partners:
TET2
Tet methylcytosine dioxygenase 2 (2001 aa)
     
   
  0.826
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit (750 aa)
     
 
  0.825
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha (658 aa)
     
   
  0.770
IDH2
Isocitrate dehydrogenase 2 (NADP+), mitochondrial; Belongs to the isocitrate and isopropylmalate dehydrogenases family (402 aa)
           
  0.751
IDH1
Isocitrate dehydrogenase 1 (NADP+), soluble; Belongs to the isocitrate and isopropylmalate dehydrogenases family (414 aa)
     
   
  0.688
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (721 aa)
     
 
  0.672
SETBP1
SET binding protein 1 (1387 aa)
       
 
  0.662
SRSF2
Serine/arginine-rich splicing factor 2b (221 aa)
     
   
  0.652
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; Aldehyde dehydrogenase 18 family, member A1; In the C-terminal section; belongs to the gamma- glutamyl phosphate reductase family (796 aa)
           
  0.646
CAMK2G
Calcium/calmodulin-dependent protein kinase II gamma (577 aa)
           
  0.643
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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