Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIGLPhosphatidylinositol glycan anchor biosynthesis class L. (274 aa)    
Predicted Functional Partners:
PIGH
Phosphatidylinositol glycan anchor biosynthesis class H.
   
 
 0.992
PIGW
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
  
 
 0.991
PIGQ
Phosphatidylinositol glycan anchor biosynthesis class Q.
   
 
 0.983
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
  
 
 0.981
PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
     
 0.977
DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
     
 0.957
PIGM
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.
     
 0.950
PIGN
Phosphatidylinositol glycan anchor biosynthesis class N.
      
 0.931
CRMP1
Collapsin response mediator protein 1.
   
  
 0.930
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
      
 0.926
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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