STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (302 aa)    
Predicted Functional Partners:
HSD17B12
Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.938
LOC102348665
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.927
ELOVL4
Elongation of very long chain fatty acids protein.
  
 
0.918
LOC102346876
Elongation of very long chain fatty acids protein.
  
 
0.918
ELOVL7
Elongation of very long chain fatty acids protein.
  
  
 
0.901
ADGRG4
Adhesion G protein-coupled receptor G4b; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.654
SERPINA10
Serpin family A member 10; Belongs to the serpin family.
   
  
 0.593
SLC6A4
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
  
 0.575
HTR3A
5-hydroxytryptamine (serotonin) receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.574
SLC27A4
Solute carrier family 27 member 4.
   
 
 0.564
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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