STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMAFNeutral sphingomyelinase activation associated factor. (912 aa)    
Predicted Functional Partners:
LOC102356355
TNFR-Cys domain-containing protein.
    
 0.882
SMPD2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.832
RACK1
Receptor for activated C kinase 1.
    
0.736
PSMB3
Proteasome subunit beta 3.
    
 
 0.596
LOC102354757
Uncharacterized protein.
    
 0.589
TNFRSF25
TNF receptor superfamily member 25.
    
 0.589
PLEKHG5
Pleckstrin homology and RhoGEF domain containing G5.
    
 0.589
H3BA84_LATCH
Uncharacterized protein.
    
 0.589
FAM110B
Family with sequence similarity 110 member B.
      
 0.542
PSMB6
Proteasome subunit beta.
      
 0.471
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.