STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLN8CLN8 transmembrane ER and ERGIC protein. (294 aa)    
Predicted Functional Partners:
GM2A
GM2 ganglioside activator.
      
 0.753
TMED4
Transmembrane p24 trafficking protein 4.
      
 0.748
CLN6
CLN6 transmembrane ER protein.
      
 0.699
CLN5
CLN5 intracellular trafficking protein.
      
 0.697
PPT1
Palmitoyl-protein thioesterase 1.
      
 0.687
MFSD8
Major facilitator superfamily domain containing 8.
      
 0.686
CLN3
Battenin.
      
 0.685
SEC24A
SEC24 homolog A, COPII coat complex component.
      
 0.664
LMF1
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
      
 0.607
SEC24C
SEC24 homolog C, COPII coat complex component.
      
 0.589
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.