STRINGSTRING
SERPINA1 protein (Latimeria chalumnae) - STRING interaction network
"SERPINA1" - Uncharacterized protein in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINA1Uncharacterized protein (430 aa)    
Predicted Functional Partners:
F2
Coagulation factor II (thrombin); Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (618 aa)
   
  0.796
HABP2
Hyaluronan binding protein 2 (480 aa)
   
  0.702
HGF
Hepatocyte growth factor (hepapoietin A; scatter factor); Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (720 aa)
   
  0.676
MST1
Macrophage stimulating 1 (707 aa)
   
  0.676
PLG
Plasminogen (725 aa)
   
  0.645
SERPINF2
Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (394 aa)
   
 
0.608
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (3259 aa)
       
  0.605
COL6A3
Collagen, type VI, alpha 3 (3169 aa)
       
  0.605
COL28A1
Collagen, type XXVIII, alpha 1 (1220 aa)
       
  0.605
COL6A5
Uncharacterized protein (1554 aa)
       
  0.605
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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