STRINGSTRING
MED8 protein (Latimeria chalumnae) - STRING interaction network
"MED8" - Mediator complex subunit 8 in Latimeria chalumnae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MED8Mediator complex subunit 8 (220 aa)    
Predicted Functional Partners:
MED10
Mediator complex subunit 10 (135 aa)
     
  0.942
MED17
Mediator complex subunit 17 (640 aa)
     
  0.934
MED18
Mediator complex subunit 18 (208 aa)
     
  0.934
MED7
Mediator complex subunit 7 (235 aa)
     
  0.931
MED11
Mediator complex subunit 11 (116 aa)
     
  0.930
MED6
Mediator complex subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (244 aa)
     
  0.928
MED14
Mediator complex subunit 14 (1445 aa)
     
  0.919
MED4
Mediator complex subunit 4 (270 aa)
     
  0.912
MED15
Mediator complex subunit 15 (753 aa)
     
  0.911
CDK8
Cyclin-dependent kinase 8 (368 aa)
     
  0.900
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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