Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
CALB2Calbindin 2. (252 aa)    
Predicted Functional Partners:
PVALB
Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).
      
 0.941
SST
Somatostatin.
   
  
 0.846
CNN2
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
 0.754
GAD1
Glutamate decarboxylase 1.
   
 
 0.720
SDF4
Stromal cell derived factor 4.
      
 0.699
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 0.667
NPY
Neuropeptide Y.
      
 0.665
CCK
Cholecystokinin.
   
  
 0.653
DCX
Uncharacterized protein.
     
 0.646
RELN
Reelin.
      
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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