STRINGSTRING
RCHY1 protein (Latimeria chalumnae) - STRING interaction network
"RCHY1" - Ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RCHY1Ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase (238 aa)    
Predicted Functional Partners:
HOXA2
Homeobox A2 (366 aa)
       
 
  0.931
TP53
Tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (401 aa)
       
  0.691
UBA52
Uncharacterized protein (128 aa)
     
  0.650
CHCHD4
Coiled-coil-helix-coiled-coil-helix domain containing 4 (142 aa)
       
 
  0.628
ZFAND4
Zinc finger, AN1-type domain 4 (738 aa)
     
  0.621
POLH
Polymerase (DNA directed), eta (729 aa)
     
  0.614
GORAB
Golgin, RAB6-interacting (378 aa)
     
 
  0.612
SPATC1L
Spermatogenesis and centriole associated 1-like (362 aa)
           
  0.578
MIB1
Mindbomb E3 ubiquitin protein ligase 1 (989 aa)
     
 
  0.566
KXD1
Ubiquitin A-52 residue ribosomal protein fusion product 1 (231 aa)
     
  0.553
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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