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PTPN6 protein (Latimeria chalumnae) - STRING interaction network
"PTPN6" - Protein tyrosine phosphatase, non-receptor type 6 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN6Protein tyrosine phosphatase, non-receptor type 6 (338 aa)    
Predicted Functional Partners:
JAK3
Janus kinase 3 (1116 aa)
     
  0.950
JAK2
Janus kinase 2 (1152 aa)
     
  0.950
JAK1
Janus kinase 1 (613 aa)
     
  0.945
GAB1
GRB2-associated binding protein 1 (534 aa)
       
  0.929
ENSLACG00000003191
Uncharacterized protein (170 aa)
     
  0.915
ERBB2
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (1250 aa)
       
  0.884
ERBB4
V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (789 aa)
       
  0.884
ERBB3
V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (1047 aa)
       
  0.884
ENSLACG00000001012
Uncharacterized protein (479 aa)
       
  0.884
CTNND1
Catenin (cadherin-associated protein), delta 1 (960 aa)
     
  0.865
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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