Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.990
H2ZX51_LATCH
Uncharacterized protein.
    
 0.989
LOC102354417
Uncharacterized protein.
    
 0.988
SYK
Tyrosine-protein kinase.
   
 0.981
KIT
KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.972
H3A807_LATCH
Uncharacterized protein.
   
 0.970
H3ACR7_LATCH
Uncharacterized protein.
   
 0.970
LYN
Tyrosine-protein kinase.
   
 0.963
H2ZZ29_LATCH
Uncharacterized protein.
   
 0.959
H3B5A0_LATCH
Fibronectin type-III domain-containing protein.
    
 
 0.945
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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