Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZZG8_LATCHTyrosine-protein kinase. (396 aa)    
Predicted Functional Partners:
YES1
Tyrosine-protein kinase.
  
 
0.937
CTNNB1
Catenin beta 1.
    
 0.933
CTNND1
Catenin delta 1.
    
 0.907
FER
Protein kinase domain-containing protein.
     
 
0.900
KIT
KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  0.764
H3A4P0_LATCH
Ig-like domain-containing protein.
 
  
   0.673
CSF1R
Colony stimulating factor 1 receptor.
   
 0.662
CRMP1
Collapsin response mediator protein 1.
    
 0.607
BIN1
Bridging integrator 1.
   
  
 0.604
H3AGX2_LATCH
Recep_L_domain domain-containing protein.
 
 
    0.594
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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