STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IST1IST1 factor associated with ESCRT-III. (260 aa)    
Predicted Functional Partners:
CHMP2A
Charged multivesicular body protein 2A.
    
 0.991
LOC102356960
Charged multivesicular body protein 3.
    
 0.990
CHMP6
Charged multivesicular body protein 6.
    
 0.980
VTA1
Vta1 domain-containing protein.
   
 
 0.974
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 0.967
VPS4A
Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.
   
 0.967
CHMP5
Charged multivesicular body protein 5.
    
 
 0.965
CHMP7
Charged multivesicular body protein 7.
    
 0.961
CHMP1B
Charged multivesicular body protein 1B.
    
 
 0.930
CHMP1A
Charged multivesicular body protein 1A.
    
 
 0.930
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.