Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (455 aa)    
Predicted Functional Partners:
SETX
Senataxin.
      
 0.848
CCNE2
Cyclin E2; Belongs to the cyclin family.
      
 0.794
ASXL1
ASXL transcriptional regulator 1.
    
 0.755
PTGES
Prostaglandin E synthase.
      
 0.753
PTGS2
Prostaglandin-endoperoxide synthase 2.
      
 0.729
PHAX
Phosphorylated adaptor for RNA export.
      
 0.697
MORN5
MORN repeat containing 5.
      
 0.684
KCNJ16
Potassium voltage-gated channel subfamily J member 16.
      
 0.676
SLC27A6
Solute carrier family 27 member 6.
     
 0.669
C1QTNF2
C1q and TNF related 2.
     
 0.667
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.