Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC102364345Ectodermal-neural cortex 3. (589 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.949
KLHL25
Kelch like family member 25.
    
   0.913
NUDCD3
NudC domain containing 3.
    
   0.796
NFE2L2
Nuclear factor, erythroid 2 like 2.
    
  0.754
HEXB
Beta-hexosaminidase.
      
 0.615
NDUFA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.580
LOC102365002
BTB domain-containing protein.
  
 
 
0.564
S100B
S100 calcium binding protein B; Belongs to the S-100 family.
      
 0.563
KLHL13
Kelch-like family member 13.
  
 
 
0.557
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.552
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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