Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
PPEF2Serine/threonine-protein phosphatase with EF-hands. (700 aa)    
Predicted Functional Partners:
NUP54
Nucleoporin 54.
      
 0.841
ONECUT2
One cut domain family member.
   
  
 0.812
FECH
Ferrochelatase; Belongs to the ferrochelatase family.
    
 
 0.803
CCNG2
Cyclin G2; Belongs to the cyclin family.
    
 0.787
CBX4
Chromobox 4.
    
 
 0.777
WDR7
WD repeat domain 7.
    
 
 0.774
RHO
Rhodopsin.
   
 0.675
LOC102347432
Rhodopsin.
   
 0.675
CBX2
Chromobox 2.
    
 
 0.599
EFCAB2
EF-hand calcium binding domain 2.
    
 0.599
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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