Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLXNA3-2Plexin A3. (1193 aa)    
Predicted Functional Partners:
PLXNA3
Sema domain-containing protein.
 
  
  0.968
NRP1
Neuropilin; Belongs to the neuropilin family.
   
 0.888
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 
0.787
SEMA3A
Semaphorin 3A; Belongs to the semaphorin family.
    
 0.772
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
    
 0.741
SEMA4B
Semaphorin 4B; Belongs to the semaphorin family.
    
 0.725
PLXND1
Plexin D1.
   
0.716
SEMA3B
Semaphorin 3B; Belongs to the semaphorin family.
    
 0.699
SEMA4A
Sema domain-containing protein; Belongs to the semaphorin family.
    
 0.695
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
    
 0.690
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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