Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZZQ4_LATCHLRRCT domain-containing protein. (200 aa)    
Predicted Functional Partners:
GP1BB
Glycoprotein Ib platelet subunit beta.
   
 0.998
YWHAZ
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.976
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.943
CHST12
Carbohydrate sulfotransferase.
    
 0.799
LOC102353339
Uncharacterized protein.
   
 0.792
MUC5AC
Uncharacterized protein.
   
 0.792
VWF
Von Willebrand factor.
   
 0.792
H3AUC5_LATCH
Uncharacterized protein.
   
 0.792
MUC19
Uncharacterized protein.
   
 0.792
H2ZS91_LATCH
Uncharacterized protein; Belongs to the peptidase S1 family.
    
 0.760
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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