Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF24Ring finger protein 24. (152 aa)    
Predicted Functional Partners:
CLRN3
Clarin 3.
      
 0.914
KCTD9
Potassium channel tetramerization domain containing 9.
      
 0.872
UBOX5
U-box domain containing 5.
    
 0.851
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
      
 0.749
CDH22
Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.643
ZNF711
Zinc finger protein 711.
    
 
 0.641
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
      
 0.641
RWDD1
RWD domain containing 1.
      
 0.631
RPS27A
Ribosomal protein S27a.
    
 0.609
PPP1R16B
Protein phosphatase 1 regulatory subunit 16B.
      
 0.608
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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