Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GFRA1Uncharacterized protein. (257 aa)    
Predicted Functional Partners:
GFRA2
GDNF domain-containing protein.
 
   
  0.903
LOC102359574
GDNF domain-containing protein.
 
      0.900
GDNF
Glial cell derived neurotrophic factor.
    
 0.896
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.874
LOC102367223
TGF_BETA_2 domain-containing protein.
    
 0.729
H3B2Y5_LATCH
TGF_BETA_2 domain-containing protein.
    
 0.729
NANOS2
Nanos-type domain-containing protein; Belongs to the nanos family.
      
 0.586
KIT
KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.519
CSF1R
Colony stimulating factor 1 receptor.
    
 0.519
DAZL
RRM domain-containing protein.
      
 0.505
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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