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CASP2 protein (Latimeria chalumnae) - STRING interaction network
"CASP2" - Caspase 2, apoptosis-related cysteine peptidase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP2Caspase 2, apoptosis-related cysteine peptidase (433 aa)    
Predicted Functional Partners:
APAF1
Apoptotic peptidase activating factor 1 (1202 aa)
     
  0.991
GABPB1
GA binding protein transcription factor, beta subunit 1 (395 aa)
     
  0.844
GABPB2
GA binding protein transcription factor, beta subunit 2 (396 aa)
     
  0.844
XIAP
Uncharacterized protein (606 aa)
     
  0.843
BIRC2
Baculoviral IAP repeat containing 2 (616 aa)
     
  0.812
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain (143 aa)
       
  0.811
BIRC6
Baculoviral IAP repeat containing 6 (4819 aa)
     
  0.801
BCL2L1
BCL2-like 1 (239 aa)
     
 
  0.768
AMY1A
Pancreatic alpha-amylase (515 aa)
     
 
  0.766
FADD
Fas (TNFRSF6)-associated via death domain (193 aa)
       
  0.762
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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