STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP2Caspase 2; Belongs to the peptidase C14A family. (433 aa)    
Predicted Functional Partners:
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain.
    
 0.962
APAF1
Apoptotic peptidase activating factor 1.
    
 0.904
LOC102363280
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 0.780
CENPN
Centromere protein N.
   
 0.771
ITGB3BP
Uncharacterized protein.
   
 0.763
CENPI
Centromere protein I.
   
 0.757
XIAP
X-linked inhibitor of apoptosis.
   
 0.750
NAIP
NLR family apoptosis inhibitory protein.
   
 0.736
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.732
CENPQ
Uncharacterized protein.
   
 0.721
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.