• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
METAP2 protein (Latimeria chalumnae) - STRING interaction network
"METAP2" - Methionine aminopeptidase 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) (494 aa)    
Predicted Functional Partners:
METAP1D
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) (339 aa)
     
 
  0.949
WDR59
WD repeat domain 59 (967 aa)
     
 
  0.863
ZC3H15
Zinc finger CCCH-type containing 15 (431 aa)
     
      0.861
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family (254 aa)
   
   
  0.794
ENSLACG00000009660
Uncharacterized protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family (266 aa)
     
   
  0.784
NMD3
60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit (487 aa)
     
 
  0.783
CHORDC1
Cysteine and histidine-rich domain (CHORD) containing 1 (337 aa)
     
   
  0.775
SRP54
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein); Belongs to the GTP-binding SRP family. SRP54 subfamily (504 aa)
   
 
  0.767
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (584 aa)
     
 
  0.703
RARS
arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (660 aa)
   
   
  0.703
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
Server load: low (10%) [HD]