Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRX2Iroquois homeobox 2. (463 aa)    
Predicted Functional Partners:
IRX3
Iroquois homeobox 3.
   
  
 0.650
HOXD12
Homeobox D12.
    
 
 0.525
IRX1
Iroquois homeobox 1.
   
  
0.506
TSHZ3
Teashirt zinc finger homeobox 3.
   
 0.489
SRF
Serum response factor.
   
 
 0.480
FOXN4
Forkhead box N4.
   
 
 0.478
DLX2
Distal-less homeobox 2.
   
 
 0.447
HOXC11
Homeobox C11.
    
 
 0.422
DLX1
Distal-less homeobox 1.
   
 
 0.418
HNF1A
HNF1 homeobox A.
    
 0.413
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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