Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (351 aa)    
Predicted Functional Partners:
COPA
Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
     
 0.566
TBCCD1
TBCC domain containing 1.
      
 0.558
PTPN3
Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
      
 0.558
ITM2B
Integral membrane protein 2B.
      
 0.549
PTPN1
Tyrosine-protein phosphatase non-receptor type.
      
 0.547
PDCD1LG2
Programmed cell death 1 ligand 2.
      
 0.499
STX7
Syntaxin 7; Belongs to the syntaxin family.
    
 0.481
GCNT1
Glucosaminyl (N-acetyl) transferase 1.
      
 0.480
IRF2BP2
Interferon regulatory factor 2 binding protein 2.
      
 0.480
RAB29
RAB29, member RAS oncogene family.
      
 0.475
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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