STRINGSTRING
PARP1 protein (Latimeria chalumnae) - STRING interaction network
"PARP1" - Poly in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP1Poly (ADP-ribose) polymerase 1 (1011 aa)    
Predicted Functional Partners:
CASP3
Caspase 3, apoptosis-related cysteine peptidase (290 aa)
     
  0.864
PARG
Poly (ADP-ribose) glycohydrolase (741 aa)
     
  0.839
CASP7
Caspase 7, apoptosis-related cysteine peptidase (313 aa)
     
  0.827
RFC3
Replication factor C (activator 1) 3, 38kDa (237 aa)
     
  0.801
RFC4
Replication factor C (activator 1) 4, 37kDa (360 aa)
     
  0.798
POLB
Polymerase (DNA directed), beta (335 aa)
     
  0.777
ENSLACG00000016571
Uncharacterized protein (541 aa)
     
  0.769
RPA2
Replication protein A2, 32kDa (257 aa)
     
  0.763
MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (710 aa)
     
  0.741
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (260 aa)
     
  0.735
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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