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MED12L protein (Latimeria chalumnae) - STRING interaction network
"MED12L" - Mediator complex subunit 12-like in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MED12LMediator complex subunit 12-like (2154 aa)    
Predicted Functional Partners:
MED13
Mediator complex subunit 13 (2186 aa)
     
  0.944
MED13L
Mediator complex subunit 13-like (2023 aa)
     
  0.935
CCNC
Cyclin C (293 aa)
     
  0.933
CDK8
Cyclin-dependent kinase 8 (368 aa)
     
  0.861
CDK19
Cyclin-dependent kinase 19 (448 aa)
     
  0.861
MED7
Mediator complex subunit 7 (235 aa)
       
  0.755
MED23
Mediator complex subunit 23 (1277 aa)
     
  0.752
MED14
Mediator complex subunit 14 (1445 aa)
     
  0.702
MED6
Mediator complex subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (244 aa)
     
 
  0.670
ENSLACG00000000654
Uncharacterized protein (99 aa)
     
  0.612
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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