Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NFKB1Nuclear factor kappa B subunit 1. (969 aa)    
Predicted Functional Partners:
NFKBIA
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.
  
0.996
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.994
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
   
 0.994
NFKBIB
NFKB inhibitor beta.
  
0.990
NFKBIE
NFKB inhibitor epsilon.
  
0.986
IL6
Uncharacterized protein.
   
 0.979
KPNA4
Importin subunit alpha; Belongs to the importin alpha family.
    
 0.956
H3B6K7_LATCH
IKKbetaNEMObind domain-containing protein.
   
 0.948
RPS3
KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.
    
 0.946
BCL3
BCL3 transcription coactivator.
  
 
0.946
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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