Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRM1Glutamate metabotropic receptor 1. (1167 aa)    
Predicted Functional Partners:
HOMER1
Homer scaffold protein 1.
    
 0.990
HOMER3
Homer scaffold protein 3b.
    
 0.981
LOC102359416
Uncharacterized protein.
    
 0.943
GNA11
G protein subunit alpha 11.
    
 0.943
HOMER2
Homer scaffold protein 2.
    
 0.935
GNAS
GNAS complex locus.
   
 0.905
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.
   
  0.903
GRIA4
Glutamate ionotropic receptor AMPA type subunit 4.
   
  
 0.690
GRASP
General receptor for phosphoinositides 1 associated scaffold protein.
    
 
 0.685
GABBR1
Gamma-aminobutyric acid type B receptor subunit 1.
   
 0.670
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]