STRINGSTRING
AMPD2 protein (Latimeria chalumnae) - STRING interaction network
"AMPD2" - Adenosine monophosphate deaminase 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMPD2Adenosine monophosphate deaminase 2 (823 aa)    
Predicted Functional Partners:
IMPDH1
IMP (inosine 5’-monophosphate) dehydrogenase 1 (515 aa)
   
  0.960
ADK
Adenosine kinase (302 aa)
     
  0.957
APRT
Adenine phosphoribosyltransferase (119 aa)
     
  0.950
ENSLACG00000017548
Adenylosuccinate synthetase ; Plays an important role in the de novo pathway of purine nucleotide biosynthesis (405 aa)
   
 
  0.950
ADSS
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis (460 aa)
   
 
  0.950
ADSSL1
Adenylosuccinate synthase like 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP (449 aa)
   
 
  0.950
HPRT1
Hypoxanthine phosphoribosyltransferase 1 (180 aa)
   
 
  0.941
ENSLACG00000005452
Uncharacterized protein (214 aa)
   
 
  0.941
ADSL
Adenylosuccinate lyase (500 aa)
     
 
  0.934
GMPR
Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (345 aa)
   
  0.934
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (11%) [HD]