Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CICCapicua transcriptional repressor. (2265 aa)    
Predicted Functional Partners:
ATXN1
Ataxin 1.
    
 
 0.985
ATXN1L
Ataxin 1 like.
    
 
 0.817
PRRC2A
Proline rich coiled-coil 2A.
   
    0.648
RBM17
RNA binding motif protein 17.
      
 0.625
NMT2
Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.
      
 0.595
PAFAH1B3
Platelet activating factor acetylhydrolase 1b catalytic subunit 3.
      
 0.568
PAFAH1B2
Platelet activating factor acetylhydrolase 1b catalytic subunit 2.
      
 0.568
PVALB
Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).
    
 
 0.472
BHLHE41
Basic helix-loop-helix family member e41.
      
 0.470
VPS26C
VPS26 endosomal protein sorting factor C.
      
 0.452
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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