Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-2NK2 homeobox 2. (278 aa)    
Predicted Functional Partners:
PAX6
Paired box 6.
   
 
 0.730
H3ACE0_LATCH
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.717
PTF1A
Pancreas associated transcription factor 1a.
    
 0.661
OLIG3
Oligodendrocyte transcription factor 3.
   
 0.656
OLIG2
Oligodendrocyte transcription factor 2.
   
 0.656
H3B9I7_LATCH
BHLH domain-containing protein.
   
 0.656
IRX3
Iroquois homeobox 3.
    
 
 0.649
RFX6
Regulatory factor X6.
      
 0.644
NKX6-2
NK6 homeobox 2.
   
  
 0.613
NKX6-1
NK6 homeobox 1.
   
  
 0.613
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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