STRINGSTRING
NKX2-2 protein (Latimeria chalumnae) - STRING interaction network
"NKX2-2" - NK2 homeobox 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-2NK2 homeobox 2 (278 aa)    
Predicted Functional Partners:
PAX6
Paired box 6 (463 aa)
     
 
  0.717
FOXA2
Forkhead box A2 (429 aa)
     
  0.663
ENSLACG00000008212
Uncharacterized protein (415 aa)
     
  0.643
FOXA1
Forkhead box A1 (439 aa)
     
  0.643
SIM1
Single-minded homolog 1 (Drosophila) (460 aa)
     
 
  0.618
NEUROD1
Neuronal differentiation 1 (340 aa)
     
   
  0.603
NEUROG3
Neurogenin 3 (237 aa)
     
 
  0.600
OLIG2
Oligodendrocyte lineage transcription factor 2 (273 aa)
       
 
  0.594
PAX7
Paired box 7 (420 aa)
     
 
  0.552
ISL1
ISL LIM homeobox 1 (356 aa)
     
 
  0.541
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (10%) [HD]