STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-2NK2 homeobox 2. (278 aa)    
Predicted Functional Partners:
PAX6
Paired box 6.
    
 
 0.566
H3ACE0_LATCH
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.564
CHRD
Chordin; Belongs to the chordin family.
      
 0.554
RFX6
Regulatory factor X6.
      
 0.541
OLIG3
Oligodendrocyte transcription factor 3.
   
 0.503
OLIG2
Oligodendrocyte transcription factor 2.
   
 0.503
H3B9I7_LATCH
BHLH domain-containing protein.
   
 0.503
H3B8Q8_LATCH
Forkhead box A3.
   
 
 0.492
NEUROG2
Neurogenin 2.
   
 0.487
NEUROG3
Neurogenin 3.
   
 0.487
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.