Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (428 aa)    
Predicted Functional Partners:
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin.
      
 0.723
TTLL1
Tubulin tyrosine ligase like 1.
   
  
 0.677
NANOS3
Nanos C2HC-type zinc finger 3; Belongs to the nanos family.
      
 0.659
DHX16
DEAH-box helicase 16.
    
 
 0.642
ELP3
Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.
      
 0.580
H3BCN4_LATCH
Tubulin tyrosine ligase-like family, member 5.
   
  
 0.545
SYCE2
Synaptonemal complex central element protein 2.
      
 0.536
TTLL4
Uncharacterized protein.
      
 0.532
LOC102364515
Uncharacterized protein.
      
 0.498
HDAC6
Histone deacetylase 6.
   
  
 0.484
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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