STRINGSTRING
PKD1L2 protein (Latimeria chalumnae) - STRING interaction network
"PKD1L2" - Polycystic kidney disease 1-like 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKD1L2Polycystic kidney disease 1-like 2 (2422 aa)    
Predicted Functional Partners:
IRF2BP2
Interferon regulatory factor 2 binding protein 2 (522 aa)
       
      0.841
ENSLACG00000002487
Uncharacterized protein (1301 aa)
     
 
  0.560
TRPM2
Transient receptor potential cation channel, subfamily M, member 2 (1473 aa)
           
  0.487
MCOLN3
Mucolipin 3 (558 aa)
           
  0.479
MCOLN2
Mucolipin 2 (538 aa)
           
  0.479
MCOLN1
Mucolipin 1 (563 aa)
           
  0.479
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Produces ATP from ADP in the presence of a proton gradient across the membrane (312 aa)
     
 
  0.461
CSNK2B
Casein kinase 2, beta polypeptide; Plays a complex role in regulating the basal catalytic activity of the alpha subunit (148 aa)
     
      0.430
IFT88
Intraflagellar transport 88 homolog (Chlamydomonas) (833 aa)
           
  0.420
STAM
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 (537 aa)
       
 
  0.403
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (13%) [HD]