Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEK4NIMA related kinase 4. (854 aa)    
Predicted Functional Partners:
RPGRIP1L
RPGRIP1 like.
   
 
 0.850
H3A652_LATCH
Uncharacterized protein.
      
 0.832
CDC25B
Cell division cycle 25B.
   
 0.731
CDC25C
Cell division cycle 25C.
   
 0.731
MTMR3
Myotubularin related protein 3.
   
   0.723
CEP162
Centrosomal protein 162.
    
   0.683
H2ZSE1_LATCH
Uncharacterized protein.
   
  
 0.680
ALG8
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
      
 0.667
SETBP1
SET binding protein 1.
    
 
 0.655
ENKUR
Enkurin, TRPC channel interacting protein.
   
 
 0.648
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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