STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYBMYB proto-oncogene, transcription factor. (761 aa)    
Predicted Functional Partners:
CREBBP
CREB binding protein.
   
 
 0.964
CEBPB
CCAAT/enhancer-binding protein.
    
 0.892
LOC102352539
Uncharacterized protein.
   
 
 0.859
LIN9
Lin-9 DREAM MuvB core complex component.
    
 0.856
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
    
 0.752
GATA2
GATA binding protein 2.
   
 0.733
SPI1
Spi-1 proto-oncogene.
     
 0.683
SPIB
ETS domain-containing protein.
     
 0.683
RAG1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
   
  
 0.635
FLI1
Fli-1 proto-oncogene, ETS transcription factor.
     
 0.621
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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