Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FSD1LFibronectin type III and SPRY domain containing 1 like. (498 aa)    
Predicted Functional Partners:
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1.
      
 0.732
RNF207
Ring finger protein 207.
      
 0.700
BCL7A
BAF chromatin remodeling complex subunit BCL7A.
      
 0.631
BSPRY
B-box and SPRY domain containing.
      
0.624
TP73
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.556
GSS
Glutathione synthetase.
      
 0.496
FSTL3
Follistatin like 3.
      
 0.486
RBCK1
IBR domain-containing protein.
    
 0.454
PDRG1
P53 and DNA damage regulated 1.
      
 0.454
METTL18
Methyltransferase like 18.
      
 0.438
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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