Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (414 aa)    
Predicted Functional Partners:
REEP5
Receptor expression-enhancing protein.
   
  
 0.760
MARCHF5
Membrane associated ring-CH-type finger 5.
   
 
 0.715
SLC66A2
Solute carrier family 66 member 2.
    
   0.685
SLC7A6OS
Solute carrier family 7 member 6 opposite strand.
      
 0.596
SLC25A48
Solute carrier family 25 member 48; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.594
ACVRL1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
  
 0.594
SLC25A16
Solute carrier family 25 member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.591
ENG
Endoglin.
      
 0.585
LOC102362671
Membrane-associated ring finger (C3HC4) 5, like.
   
 
 0.580
TK2
Thymidine kinase 2.
      
 0.537
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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