Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NKD2NKD inhibitor of WNT signaling pathway 2. (387 aa)    
Predicted Functional Partners:
DVL3
Dishevelled segment polarity protein 3.
    
 0.978
DVL2
Dishevelled segment polarity protein 2.
    
 0.978
DVL1
Dishevelled segment polarity protein 1.
    
 0.978
NKD1
NKD inhibitor of WNT signaling pathway 1.
     
 
0.900
RFX4
Regulatory factor X4.
      
 0.656
MORN3
MORN repeat containing 3.
      
 0.592
NOTUM
Notum, palmitoleoyl-protein carboxylesterase.
   
  
 0.580
CTNNB1
Catenin beta 1.
    
 
 0.571
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.540
GPATCH3
G-patch domain containing 3.
      
 0.531
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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