Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRMD3FERM domain containing 3. (552 aa)    
Predicted Functional Partners:
LOC102359416
Uncharacterized protein.
      
 0.641
GNA11
G protein subunit alpha 11.
      
 0.641
ENOX1
Ecto-NOX disulfide-thiol exchanger 1.
      
 0.638
RASEF
RAS and EF-hand domain containing.
      
 0.633
ISCA1
Iron-sulfur cluster assembly 1.
      
 0.630
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 
 0.592
DCTN3
Dynactin subunit 3.
      
 0.564
NOL6
Nucleolar protein 6.
      
 0.561
DCAF12
DDB1 and CUL4 associated factor 12.
      
 0.543
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.543
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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