Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYTL3Synaptotagmin like 3. (625 aa)    
Predicted Functional Partners:
RAB27B
RAB27B, member RAS oncogene family.
    
 0.891
RAB27A
RAB27A, member RAS oncogene family.
    
 0.891
AP1B1
AP complex subunit beta.
     
 0.779
MIDN
Midnolin.
      
 0.728
SIK1
Salt-inducible kinase 1.
      
 0.656
ZMAT5
Zinc finger matrin-type 5.
      
 0.641
RSPH3
Radial spoke head 3.
      
 0.629
CCDC157
Coiled-coil domain containing 157.
      
 0.574
RIMS4
Regulating synaptic membrane exocytosis 4.
     
 0.552
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.548
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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