ARRB1 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ARRB1

Arrestin beta 1. (394 aa)

Predicted Functional Partners:

GAK

0.966

ITSN2

0.965

CLTCL1

0.793

CLTC

0.793

GNAT3

0.786

NUDC

0.748

CLHC1

0.718

RHO

0.701

LOC102347432

0.701

SMO

0.690

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB1	CLHC1	ENSLACP00000003241	ENSLACP00000022627	Arrestin beta 1.	Clathrin heavy chain linker domain-containing protein 1.	0.718
ARRB1	CLTC	ENSLACP00000003241	ENSLACP00000011035	Arrestin beta 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.793
ARRB1	CLTCL1	ENSLACP00000003241	ENSLACP00000010273	Arrestin beta 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.793
ARRB1	GAK	ENSLACP00000003241	ENSLACP00000006296	Arrestin beta 1.	J domain-containing protein.	0.966
ARRB1	GNAT3	ENSLACP00000003241	ENSLACP00000005214	Arrestin beta 1.	G protein subunit alpha transducin 3.	0.786
ARRB1	ITSN2	ENSLACP00000003241	ENSLACP00000013254	Arrestin beta 1.	Intersectin 2.	0.965
ARRB1	LOC102347432	ENSLACP00000003241	ENSLACP00000018849	Arrestin beta 1.	Rhodopsin.	0.701
ARRB1	NUDC	ENSLACP00000003241	ENSLACP00000013237	Arrestin beta 1.	Nuclear distribution C, dynein complex regulator.	0.748
ARRB1	RHO	ENSLACP00000003241	ENSLACP00000014823	Arrestin beta 1.	Rhodopsin.	0.701
ARRB1	SMO	ENSLACP00000003241	ENSLACP00000002758	Arrestin beta 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.690
CLHC1	ARRB1	ENSLACP00000022627	ENSLACP00000003241	Clathrin heavy chain linker domain-containing protein 1.	Arrestin beta 1.	0.718
CLHC1	GAK	ENSLACP00000022627	ENSLACP00000006296	Clathrin heavy chain linker domain-containing protein 1.	J domain-containing protein.	0.999
CLHC1	ITSN2	ENSLACP00000022627	ENSLACP00000013254	Clathrin heavy chain linker domain-containing protein 1.	Intersectin 2.	0.991
CLTC	ARRB1	ENSLACP00000011035	ENSLACP00000003241	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Arrestin beta 1.	0.793
CLTC	GAK	ENSLACP00000011035	ENSLACP00000006296	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	J domain-containing protein.	0.999
CLTC	ITSN2	ENSLACP00000011035	ENSLACP00000013254	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Intersectin 2.	0.991
CLTCL1	ARRB1	ENSLACP00000010273	ENSLACP00000003241	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Arrestin beta 1.	0.793
CLTCL1	GAK	ENSLACP00000010273	ENSLACP00000006296	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	J domain-containing protein.	0.999
CLTCL1	ITSN2	ENSLACP00000010273	ENSLACP00000013254	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Intersectin 2.	0.991
GAK	ARRB1	ENSLACP00000006296	ENSLACP00000003241	J domain-containing protein.	Arrestin beta 1.	0.966