Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASSF6Ras association domain family member 6. (319 aa)    
Predicted Functional Partners:
LOC102346204
Protein kinase domain-containing protein.
    
 0.784
STK4
Serine/threonine kinase 4.
    
 0.784
STK3
Serine/threonine kinase 3.
    
 0.742
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 
 0.709
AMER2
APC membrane recruitment protein 2.
    
 
 0.643
RASSF10
Ras association domain family member 10.
   
  
 0.605
RASSF9
Ras association domain family member 9.
   
  
 0.595
USP10
Ubiquitin carboxyl-terminal hydrolase.
      
 0.593
INSYN2B
Inhibitory synaptic factor family member 2B.
      
 0.592
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
   
  
 0.589
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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