Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102354037Hairy-related 8.2. (222 aa)    
Predicted Functional Partners:
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.646
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.646
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
 0.636
LOC102367663
Achaete-scute family bHLH transcription factor 1b.
   
 0.635
FANCF
FA complementation group F.
    
   0.621
FANCL
FA complementation group L.
    
   0.621
LOC102353186
Hes family bHLH transcription factor 6.
    
 
 0.588
SIRT1
Sirtuin 1.
    
 
 0.544
TLE3
TLE family member 3, transcriptional corepressor.
    
 0.515
LOC102356408
Uncharacterized protein.
    
 0.515
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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